Serotonin reuptake inhibitors, Raynaud's phenomenon and erythromelalgia.
نویسندگان
چکیده
(Letter to the Editor) SIR, We read with great interest the report by Coleiro et al. [1] describing a pilot study on the tolerability and efficiency of fluoxetine for the treatment of Raynaud's phenomenon. This study confirmed previous case reports suggesting the usefulness of selective serotonin reuptake inhibitors (SSRIs) in the management of Raynaud's phenomenon [2, 3]. Here we describe for the first time two patients who experienced, when given SSRIs, disappearance of Raynaud's phenomenon but occurrence of erythromelalgia.
منابع مشابه
Treatment of Raynaud's phenomenon with escitalopram.
Serotonin has been shown to play a significant role in diseases related to vascular dysregulation like Raynaud’s phenomenon (Hollenberg, 1988), erythromelalgia (Rudikoff and Jaffe, 1997),migraine (Bonvento et al., 1991) and perimenopausal hot flushes (Berendsen, 2000). In recent years there have been several reports on the efficacy of the selective serotonin reuptake inhibitors (SSRIs) fluoxeti...
متن کاملTreatment of erythromelalgia with a serotonin/noradrenaline reuptake inhibitor.
(Letter to the Editor) SIR, Erythromelalgia is an unusual disorder characterized by the triad of red, hot and painful extremities. The symptoms are exacerbated by heat and improved by cold. Its aetiology is not fully understood. Numerous different medications including aspirin, gabapentin, amitriptyline, benzodiazepines and opiates have been used in attempts to treat the symptoms of erythromela...
متن کاملTreatment of Raynaud's phenomenon with the selective serotonin reuptake inhibitor fluoxetine.
OBJECTIVE To compare fluoxetine, a selective serotonin reuptake inhibitor, with nifedipine as treatment for primary or secondary Raynaud's phenomenon. METHODS Twenty-six patients with primary and 27 patients with secondary Raynaud's phenomenon were assigned randomly to receive 6 weeks of treatment with fluoxetine (20 mg daily) or nifedipine (40 mg daily). Following a 2-week washout period, ea...
متن کاملRisperidone Related Raynaud’s Phenomenon: An Adolescent Case
Raynaud's phenomenon is a recurrent vasospastic condition with reducing in peripheral blood flow due to cold, or emotional stress. White, blue and red discolorations occur during the attacks. Serotonin reuptake inhibitors, psychostimulants, and aripiprazole are reported to be related with Raynaud's phenomenon. Risperidone is an atypical antipsychotic drug with dopaminergic and serotonergic effe...
متن کاملErythromelalgia: response to serotonin reuptake inhibitors.
Erythromelalgia is a painful disorder of the extremities characterized by redness, swelling, a burning sensation, and an increase in skin temperature exacerbated by exposure to heat. 1 An early description was reported by Mitchell 2 in 1878. He coined the term erythromelalgia to denote the clinical features of redness (erythros), involvement of the extremities (melos), and the symptom of pain (...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Rheumatology
دوره 42 4 شماره
صفحات -
تاریخ انتشار 2003